Heptanoic acid, 7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-, (3R,5R)- - Names and Identifiers
Name | (3R,5R)-7-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic aci
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Synonyms | ATV imp F Atorvastatin EP IMpurity F Atorvastatin EP Impurity F Sodium Salt Atorvastatin Calcium Hydrate impurity F Atorvastatin IMpurity F (AMide IMpurity) SodiuM Salt (3R,5R)-7-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic aci (3R,5R)-7-[[(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoyl]amino]-3,5-dihydroxyheptanoic acid Heptanoic acid, 7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-, (3R,5R)-
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CAS | 887196-24-9
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Heptanoic acid, 7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-, (3R,5R)- - Physico-chemical Properties
Molecular Formula | C40H48FN3O8
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Molar Mass | 717.82 |
Density | 1.28±0.1 g/cm3(Predicted) |
Boling Point | 934.8±65.0 °C(Predicted) |
pKa | 4.30±0.10(Predicted) |
Storage Condition | -20℃ |
Heptanoic acid, 7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-, (3R,5R)- - Introduction
Atorvastatin calcium is a drug for the treatment of high cholesterol and cardiovascular disease. (3R,5R)-7-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1h-yrrol-1-yl)-3,5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic aci is an impurity in its structure.
Properties:(3R,5R)-7-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3, the chemical name of 5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic aci is (((3R,5R)-7-((3R,5R)-7-(2-(4-fluorophenyl))-5-Isopropyl-3-phenyl-4-phenylcarboxamide)-3,5-dihydroxyheptanoyl)-3,5-dihydroxyheptanoic acid. It is an organic compound whose chemical properties can be classified as ketones and esters. Specific physical properties such as melting point, boiling point and solubility need to be determined by experiments.
Purpose: Atorvastatin calcium is a popular lipid-lowering drug used to lower blood cholesterol levels and prevent the development of cardiovascular disease. However,(3R,5R)-7-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic aci has no clear medical application.
preparation method: since (3R,5R)-7-((3R,5R)-7-(2-(4-fluorophenyl)-5-isoppropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic aci is part of the structure of atorvastatin calcium, so it can be produced as a synthetic intermediate of atorvastatin calcium. The specific preparation method can be realized by using organic synthesis technology in chemical laboratory. However, due to the complexity and confidentiality of drug synthesis, detailed preparation protocols are often protected trade secrets.
Safety Information:(3R,5R)-7-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3, the specific toxicity and safety information of 5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic aci requires further research and experimental verification. Generally speaking, as a synthetic intermediate of a drug, its safety should be properly controlled and evaluated to avoid unnecessary harm to the human body. During use and handling, correct laboratory practices must be followed and appropriate personal protective measures must be taken to ensure the safety of personnel. If necessary, the operation should be carried out under the guidance of professional personnel.
Last Update:2024-04-09 21:04:16